FLOWCELL: A SIMPLE SOLUTION TO THE FLOW PROCESS

FLOWCELL

RAMAN FLOW CELL

A sophisticated solution for building highly reliable MarqMetrix® Raman measurements into a continuous flow process, the FlowCell BallProbe® can be directly added into the flow path using common, industry-standard connections. This eliminates the complications of designing a system using proprietary hardware or attempting to port an immersion Raman probe into the flow path.

THE FLOWCELL ADVANTAGE

  • BallProbe technology integrated directly into the flow path
  • Flow cell probes available in two high-performance packages:
    • 200°C, 500psi with a perfluoroelastomer seal
    • 350°C, 2000psi with a gold seal
  • Internal volume: ~180uL
  • Custom flow cell probes: Available with higher pressure/temperature ratings, different materials, custom connections, and internal volumes

 

Corrosion-resistant

The probe body is constructed of Hastelloy C22 alloy, a nickel-based alloy widely considered the most corrosion-resistant steel.

Pairing capabilities

Designed for use with the MarqMetrix® Fiber BallProbe®, but this probe may also be paired with third-party fiber probes compatible with a half-inch cylindrical connection.

 

Spec Sheets

marqmetrix flowcell
marqmetrix flowcell connector

FLOWCELL IN ACTION

 

Continuous flow drug manufacturing

The challenge

In continuous flow drug manufacturing, monitoring the reaction progress in real-time is key to efficiency and cost savings, whether in manufacturing or research.

How FlowCell was used

Using FlowCell, Raman measurements were integrated directly into the flow paths, allowing quantitative assessment of inputs, intermediates, and products.

Why it matters

Real-time chemical feedback allows for the complex design of experiments during the drug development phase. FlowCell measurements allow researchers to dynamically optimize quality and yield over a wide range of control parameters (flow rates, temperatures, mixing rates, etc.)

Continuous flow explosive manufacturing

The challenge

Explosive manufacturing requires precise control over temperature and mixing while working with hazardous materials. Furthermore, the environment tends to be highly corrosive.

How FlowCell was used

FlowCell was integrated into the manufacturing stream, offering unparalleled control of chemistry — critical when manufacturing explosives.

Why it matters

FlowCell performs well at the limited rate of manufacturing used to prevent the buildup of large volumes of potential explosive or hazardous intermediates. This probe is also compatible with the highly corrosive chemistries involved.

 

MarqMetrix All-In-One

RELATED PRODUCTS​

MarqMetrix® All-In-One Process Raman System: A single-unit spectrometer, laser, and acquisition computer.

Performance BallProbe®: A immersion contact probe designed to withstand moderate chemical environments in laboratory and industrial settings.

Fiber BallProbe®:  A filtered fiber optic interface specifically designed for the MarqMetrix BallProbe® and MarqMetrix All-In-One Process Raman system.

 

MarqMetrix is proud to now be part of Thermo Fisher Scientific. Read More